Effects of Dioxins

• Multiple Effects

• In Multiple Tissues

• Of Both Sexes

• Of Multiple Species

• Throughout the Vertebrate Kingdom

Molecular Changes ——> Biochemical Alterations

Altered Metabolism ——> Cellular Effects

Altered Proliferation / Differentiation ——> Tissue/Organ Effects

Altered Homeostasis ——> Overt Toxicity (Wasting/Death)

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