Dioxins Perturb Every Hormone System Investigated

Receptor Level

Hormone Anabolism/Catabolism

Protein Binding (Serum Transport)

Dioxins Perturb Multiple Growth Factor Systems

Vitamin A, TGF Alpha and Beta, Cytokines…

Dioxins Alter

Gene Expression

Signal Transduction (phosphorylation; Calcium Mobilization)

Cell Proliferation/Apoptosis

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